2492 Walnut Ave, Suite 100
Tustin, CA 92780
Office: 714-709-8000

DHH-B: The Possible Benefits Of Honokiol On Your Neuroaffect Circuit

An image of a magnolia grandiflora plantDHH-B is a higher concentration of honokiol, a derivative made from the bark of the Magnolia grandiflora plant which is indigenous to Japan. Traditionally used in Asian holistic practices, DHH-B is used as a remedy to combat anxiety, fever, headaches, and nervous conditions. Other Magnolia species, such as Magnolia dealbata, a native to Mexico, have also been found to have similar properties as those derived from the Japanese Magnolia.

Although traditionally seen as an herbal remedy, much research into Magnolia and its various applications prove that claims from the traditional medical community may be true. Thus far, DHH-B, according to research, may possess various beneficial pharmacological activities. These include antibacterial, anticancer, anti-inflammatory, antioxidant, antidepressant, and beneficial Neuroaffect properties.

For the purposes of this article, we will concentrate on the beneficial Neuroaffect properties of DHH-B.

The Neuroaffect Properties of DHH-B

The use of DHH-B has gained traction across the globe due to its neuroprotective properties. In the brain, DHH-B can cross the blood-brain area. This enables it to exert an anti-tumor effect on your central nervous system. But this is not the only way in which DHH-B affects the brain. The various Neuroaffect properties shown by DHH-B may have a positive potential in addressing such issues as epilepsy, cognitive disorders like Alzheimer’s disease, pain, anxiety, and cerebrovascular injury.

Currently, the administration of DHH-B includes oral, intravenous, and topical applications.

Research Indicates The Following Potential Neuroaffect Actions Of DHH-B

  • The compound may help mitigate the side-effects associated with stroke or seizure while improving memory. According to research, an intravenous DHH-B infusion may significantly decrease the resulting symptoms of these two issues, including physical and mental performance.
  • DHH-B may promote healthy connections between nerve cells. In doing so, it may play a role in the health of the immune system and the oxidation process. This could imply that DHH-B may help prevent neuronal damage.
  • Research also shows that DHH-B may inhibit inflammatory reactions in the brain that could negatively affect proper Neuroaffect function.
  • Regarding its potential in those suffering from epilepsy and other disorders involving seizures, DHH-B may play a beneficial role as it may both inhibit seizures and increase your seizure threshold.
  • When it comes to age-related cognitive decline, results thus far seem promising. Tests designed to evaluate learning and memory found that DHH-B may slow down age-related memory and learning issues due to the aging process. In addition to this, it may also decrease reactive oxygen species (ROS). ROS is the byproduct of normal oxygen metabolism in your body and plays a role in cell signaling and keeping your body in balance. However, too much ROS may cause oxidative stress that may lead to lipid, protein, and DNA damage. By reducing your body’s ROS production, decreasing calcium levels in your cells, and inhibiting DNA damage, DHH-B may help with the detoxification process at a cellular level. This suggests its effectiveness in combating neurodegenerative disorders.

The Effect Of DHH-B On Anxiety

An image of a woman sitting down with her fingers claspedAnxiety often leads to depression, one of the most common psychological disorders around. Research suggests that DHH-B, in low doses, can help address anxiety issues. This may result from its interaction with your brain’s GABA receptor, a protein that acts as an inhibitory neurotransmitter in your central nervous system. Its interaction with the GABA receptor may help anxiety issues without having the same side-effects as conventional medications.

Anxiety is also a condition related to sleep issues. Getting enough sleep is important for your body’s ability to heal itself. Too little sleep does not interfere with these healing processes but may also result in cognitive and other psychological issues. Studies suggest that DHH-B may have an overall beneficial effect on sleep quality and promote sleep in those finding it difficult to fall asleep at night.

The Effect Of DHH-B On Inflammation And Pain

Inflammation is your body’s response to any perceived health issue. It may also affect your Neuroaffect circuit which means it would also affect your brain function and response. Inflammation is often accompanied by pain. It is also part of your immune response.

DHH-B has an immunomodulatory effect that helps control chronic inflammation and pain, according to studies. It may also have pain-blocking properties. DHH-B is also an immune modulator and helps the body immune function.

Risk Factors Associated With DHH-B

Although studies find that DHH-B may have many positive benefits for the human condition in general, and your Neuroaffect circuit in particular, and has been part of traditional medicine for thousands of years, one needs to remember the most studies thus far have been on animals. Research does, however, show that DHH-B may have many benefits that, once testing has been done on humans, could be used for many health applications.

But as with just about any form of medicine or supplement, DHH-B may have some measure of risk involved. These include, amongst others:

  • An increased risk of bleeding
  • Possible neurotoxicity when taken at high doses

Studies suggest DHH-B is an arterial thrombosis inhibitor. It thus probably not suitable for use in cases where bleeding or hemorrhage is a possibility. Using it on those with hemophilia or who use blood-thinning medications may thus also not be advisable.

Finally, do not take DHH-B if you need to stay awake like when driving, for example. This is because it may provoke sleep.

Importance Of A Healthy Neuroaffect Circuit

Your Neuroaffect Circuit is one of the components of your NeuroEndoMetabolic (NEM) Stress Response and made up of your brain, your autonomic nervous system, and your microbiome. It governs the physical aspects of brain health that could influence your psychological responses.

Your autonomic nervous system (ANS) is made up of three parts, each with its own individual function. Generally speaking, your ANS is tasked with triggering your body’s ‘flight or fight’ response when in the presence of danger and the accompanying stress. This response starts in your brain’s hypothalamus which is part of the Hypothalamic-Pituitary-Adrenal (HPA) axis. Communication via the HPA and different components of the ANS takes place by means of chemical messengers called neurotransmitters. These messages travel from one cell to another via a series of chemically controlled synapses.

An increase in cortisol production, released by the adrenal glands, forms part of this ‘fight or flight’ response. If stress does not decrease, the adrenals keep up their elevated cortisol production. This could, in the long term, have devastating consequences for your general health and wellbeing because constantly elevated cortisol production is accompanied by a decrease or shut down of numerous bodily functions.

Functions Affected

An image of a colorful brain diagramSome of the functions affected include various brain functions due to factors like hormone imbalance and impaired neuron function. It could also result in adrenal fatigue. Many of the chemical messengers used by your brain are also hormones. Imbalanced neurotransmitters could result in numerous health issues. These health issues include anxiety, depression, impaired cognitive function, and many others.

When taking into account the many beneficial properties of DHH-B, those associated with proper brain function include its ability to fight toxins and inflammation. Inflammation and toxin buildup may happen due to your body going through a continuous NEM response with constantly elevated cortisol levels. At the same time, however, DHH-B’s neuromodulating properties support neurotransmissions, by sending chemical messages between cells and organ systems.

In Closing

Although DHH-B in its herbal form has been used in traditional healing for thousands of years, modern science has only recently begun to look into the properties and possible benefits it poses for modern medicine. Although most studies thus far have been conducted on animals, the results look promising for use in a variety of human health issues and applications. However, always consult an experienced practitioner before starting DHH-B as you have to beware of paradoxical reactions in adrenal fatigue sufferers.

The key takeaways on DHH-B are as follows:

  1. DHH-B holds many possible benefits for those suffering from neurological conditions.
  2. It may aid those with anxiety and depression or those with sleep issues.
  3. Those with health issues related to bleeding may want to think twice about using DHH-B.
© Copyright 2022 Lam Clinic. All rights reserved.

Key Question

While DHH-B could not cure adrenal fatigue, it could most certainly offer support in fighting the condition. This is because of its beneficial action with regards to brain health and function. By supporting brain health and function, it goes to follow that adrenal health also sees a positive impact.

2492 Walnut Ave, Suite 100
Tustin, CA 92780
Monday: 8:00 a.m. to 5:00 p.m.
Tuesday: 8:00 a.m. to 5:00 p.m.
Wednesday: 8:00 a.m. to 5:00 p.m.
Thursday: 8:00 a.m. to 5:00 p.m.
Friday: 8:00 a.m. to 5:00 p.m.
Saturday: Closed
Sunday: Closed
Schedule Your Appointment ›New Patient: 000-000-0000 Current Patient: 714-709-8000
About UsMeet the TeamOffice DetailsContact UsFAQPatient Portal LoginPatient Reviews
(Educational resources courtesy of Dr Lam Coaching, a telephone based nutritional coaching service operated independently from Lam Clinc)
Dr. Lam CoachingBooksMedia for PurchaseMobile AppBlog