Therapeutic Plasma Exchange (TPE) at Lam Clinic
Lowering the Inflammatory Load So Your Body Can Finally Recover
Become a Patient TodayCall Now 714-709-8000
If you are stuck in cycles of inflammation, weakness, and mental fog, it can be exhausting to keep trying medications without steady relief.
At Lam Clinic, we evaluate whether Therapeutic Plasma Exchange (TPE) fits your case.
In certain autoimmune and post-viral conditions, plasma can hold antibodies and inflammatory proteins. TPE filters plasma and returns blood cells with clean replacement fluid.
Is Therapeutic Plasma Exchange (TPE) Right for You?
You may benefit if you are experiencing:
- Autoimmune or inflammatory flares that are not settling with standard treatment
- Persistent fatigue, weakness, or “crash” cycles
- Brain fog, slowed thinking, or trouble concentrating
- Ongoing pain or body inflammation that feels hard to calm
- Post-viral symptoms that remain active for months
- Lab patterns suggesting high inflammatory or antibody burden
- Very high triglycerides or hyperviscosity concerns that need faster support
You may be a good fit if you are looking for:
- A physician-led evaluation to determine whether TPE truly fits your case
- A way to lower inflammatory load when antibodies or proteins may be driving symptoms
- A structured plan that coordinates TPE with your current specialists and medications
- Clear monitoring of symptoms and key lab markers over time
- A cautious, safety-first approach with supportive care before and after each session
- Realistic expectations, including that TPE is one part of a broader treatment plan
What to Expect When You Work With Us

TPE care at Lam Clinic is physician-led, paced, and safety-focused. We take time to understand what is driving your symptoms, review what you have already tried, and determine whether TPE fits into a coordinated plan.
- First visit: A comprehensive review of your symptoms, diagnosis history, prior labs, medications, and current care team
- Testing (when needed): Targeted, question-based testing to clarify inflammatory patterns, antibody burden, clotting risk, and organ function
- Your plan: Clear guidance on preparation, session timing, and supportive lifestyle steps, with therapies added only when they match your findings
- Follow-up: Symptom tracking and key lab monitoring, with adjustments based on response and coordination with your other physicians
How Therapeutic Plasma Exchange (TPE) Works at Lam Clinic by Using the LAM Method™
TPE is not approached as a stand-alone procedure. At Lam Clinic, we use the LAM Method™ to determine whether plasma exchange fits your physiology, when it is most appropriate, and how to support you before, during, and after treatment. This method follows three healing phases: Learn the Why, Address the Root, and Maximize Longevity. Here is how we apply the LAM Method™ to testing:

Phase 1 of LAM Method™
Learn the Why
We start by understanding the pattern behind your symptoms. Your physician reviews your timeline, flare triggers, current medications, and prior workups.
When needed, we order targeted testing to clarify antibody burden, inflammatory activity, clotting risk, lipid patterns, and organ function so TPE is considered for clear clinical reasons.
Phase 2 of LAM Method™
Address the Root
If TPE is a good fit, we build a plan that lowers inflammatory load while supporting the systems that help you recover. This may include:
- Lifestyle targets that protect energy, sleep, and nervous system stability
- Nutritional strategies that support immune balance and steadier recovery, alongside supplements our team has vetted for quality and fit. Browse our recommendations at Dr. Lam’s Online Store
- Therapies when appropriate, including TPE timing, supportive IV care, and mineral support based on your response and safety needs


Phase 3 of LAM Method™
Maximize Longevity
After the initial series, we track trends over time. We monitor how you feel day to day, review follow-up labs when appropriate, and adjust the plan so improvements are more stable.
If further TPE is needed, it is scheduled thoughtfully and coordinated with your broader medical care.
Why Patients Choose Lam Clinic for Therapeutic Plasma Exchange

Therapeutic Plasma Exchange at Lam Clinic is physician-led and carefully integrated into your broader medical care.
We combine conventional medicine with functional and systems-based evaluation so decisions about TPE are grounded in both safety and clinical context.
Patients choose Lam Clinic because we:
- Provide physician-led oversight before, during, and after each TPE series
- Integrate conventional standards with functional medicine insight when reviewing complex cases
- Carefully review your medications, prior testing, and specialist evaluations before recommending treatment
- Coordinate with your existing care team and do not replace your primary care physician
- Offer long-term, structured follow-up with trend tracking and thoughtful adjustments over time
Frequently Asked Questions
What is the difference between TPE and dialysis?
Dialysis removes waste when the kidneys are not working properly. Therapeutic Plasma Exchange removes and replaces the plasma portion of blood to lower harmful antibodies, inflammatory proteins, or certain circulating toxins. The goals and medical indications are different.
How many TPE sessions will I need?
The number of sessions depends on your diagnosis, symptom severity, and response. Acute cases may require a short series of 3 to 5 treatments. Chronic or autoimmune conditions often begin with 5 to 7 sessions, then adjust based on symptom trends and follow-up labs.
Is TPE safe, and what should I expect during treatment?
When performed by trained medical providers, TPE is generally well tolerated. During treatment, your blood circulates through a machine that separates and replaces plasma. You may feel cool or notice mild tingling from temporary calcium shifts. We monitor vital signs closely throughout your session.
Do you offer virtual visits and where are you located?
Yes. We offer secure telehealth visits for patients worldwide, along with in-person care at our clinic in Tustin, California. Many patients visit us from across Orange County, including Irvine, Santa Ana, Orange, Costa Mesa, and Anaheim.
Do you accept insurance?
We accept most PPO insurance plans. Coverage varies by plan. We do not accept Medicare, Medicaid/Medi-Cal, or HMOs. When something isn’t covered, we’ll explain costs upfront and help you prioritize what matters most.
Have You Been Stuck in Flares That Won’t Fully Settle?
If you are living with ongoing inflammation, fatigue, or brain fog despite doing “everything right,” we can help you understand whether TPE is appropriate and how it may fit into a broader, physician-led plan.
Services We Are Known for
Explore our other services to heal,
feel your best and stay well for life.
Services We Are Known for
