Fatigue & Stress Response

For those who feel tired all the time, overwhelmed, or wired but tired—this may be more than stress. We look deeper at adrenal and hormonal imbalances to restore steady energy and resilience.

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Common Health Issues

Hormones & Reproductive Health

For women dealing with cycles, menopause, fertility, or hormone-driven symptoms.

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Common Health Issues

Gut & Digestive Issues

For those struggling with bloating, pain, IBS, or food reactions.

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Common Health Issues

Brain, Mood & Sleep

For brain fog, anxiety, poor sleep, or emotional ups and downs.

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Common Health Issues

Heart & Circulation

For blood pressure issues, poor circulation, palpitations, and heart concerns.

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Common Health Issues

Weight, Blood Sugar & Metabolism

For weight issues, blood sugar crashes, and sluggish metabolism.

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Common Health Issues

Immune & Inflammation

For chronic inflammation, flare-ups, and immune dysregulation.

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Common Health Issues

Longevity & Anti-Aging

Optimizing your health for lifespan and healthspan.

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Common Health Issues

Conditions We Treat

Therapeutic Plasma Exchange (TPE) at Lam Clinic

Lowering the Inflammatory Load So Your Body Can Finally Recover

Become a Patient Today
Call Now 714-709-8000

If you are stuck in cycles of inflammation, weakness, and mental fog, it can be exhausting to keep trying medications without steady relief.

At Lam Clinic, we evaluate whether Therapeutic Plasma Exchange (TPE) fits your case.

In certain autoimmune and post-viral conditions, plasma can hold antibodies and inflammatory proteins. TPE filters plasma and returns blood cells with clean replacement fluid.

Is Therapeutic Plasma Exchange (TPE) Right for You?

You may benefit if you are experiencing:

  • Autoimmune or inflammatory flares that are not settling with standard treatment
  • Persistent fatigue, weakness, or “crash” cycles
  • Brain fog, slowed thinking, or trouble concentrating
  • Ongoing pain or body inflammation that feels hard to calm
  • Post-viral symptoms that remain active for months
  • Lab patterns suggesting high inflammatory or antibody burden
  • Very high triglycerides or hyperviscosity concerns that need faster support

You may be a good fit if you are looking for:

  • A physician-led evaluation to determine whether TPE truly fits your case
  • A way to lower inflammatory load when antibodies or proteins may be driving symptoms
  • A structured plan that coordinates TPE with your current specialists and medications
  • Clear monitoring of symptoms and key lab markers over time
  • A cautious, safety-first approach with supportive care before and after each session
  • Realistic expectations, including that TPE is one part of a broader treatment plan

What to Expect When You Work With Us

TPE care at Lam Clinic is physician-led, paced, and safety-focused. We take time to understand what is driving your symptoms, review what you have already tried, and determine whether TPE fits into a coordinated plan.

  • First visit: A comprehensive review of your symptoms, diagnosis history, prior labs, medications, and current care team
  • Testing (when needed): Targeted, question-based testing to clarify inflammatory patterns, antibody burden, clotting risk, and organ function
  • Your plan: Clear guidance on preparation, session timing, and supportive lifestyle steps, with therapies added only when they match your findings
  • Follow-up: Symptom tracking and key lab monitoring, with adjustments based on response and coordination with your other physicians
See What Working With Us Looks Like

How Therapeutic Plasma Exchange (TPE) Works at Lam Clinic by Using the LAM Method™

TPE is not approached as a stand-alone procedure. At Lam Clinic, we use the LAM Method™ to determine whether plasma exchange fits your physiology, when it is most appropriate, and how to support you before, during, and after treatment. This method follows three healing phases: Learn the Why, Address the Root, and Maximize Longevity. Here is how we apply the LAM Method™ to testing:

LAM Method - Learn the Why

Phase 1 of LAM Method™

Learn the Why

We start by understanding the pattern behind your symptoms. Your physician reviews your timeline, flare triggers, current medications, and prior workups.

When needed, we order targeted testing to clarify antibody burden, inflammatory activity, clotting risk, lipid patterns, and organ function so TPE is considered for clear clinical reasons.

See the Labs We Use

Phase 2 of LAM Method™

Address the Root

If TPE is a good fit, we build a plan that lowers inflammatory load while supporting the systems that help you recover. This may include:

  • Lifestyle targets that protect energy, sleep, and nervous system stability
  • Nutritional strategies that support immune balance and steadier recovery, alongside supplements our team has vetted for quality and fit. Browse our recommendations at Dr. Lam’s Online Store
  • Therapies when appropriate, including TPE timing, supportive IV care, and mineral support based on your response and safety needs
LAM Method - Address the Root
LAM Method - Maximize Longevity

Phase 3 of LAM Method™

Maximize Longevity

After the initial series, we track trends over time. We monitor how you feel day to day, review follow-up labs when appropriate, and adjust the plan so improvements are more stable.

If further TPE is needed, it is scheduled thoughtfully and coordinated with your broader medical care.

Explore the LAM Method™ in Detail

Why Patients Choose Lam Clinic for Therapeutic Plasma Exchange

Dr. Carrie Lam, Dr. Michael Lam, & Dr. Jeremy Lam

Therapeutic Plasma Exchange at Lam Clinic is physician-led and carefully integrated into your broader medical care.

We combine conventional medicine with functional and systems-based evaluation so decisions about TPE are grounded in both safety and clinical context.

Patients choose Lam Clinic because we:

  • Provide physician-led oversight before, during, and after each TPE series
  • Integrate conventional standards with functional medicine insight when reviewing complex cases
  • Carefully review your medications, prior testing, and specialist evaluations before recommending treatment
  • Coordinate with your existing care team and do not replace your primary care physician
  • Offer long-term, structured follow-up with trend tracking and thoughtful adjustments over time
Meet Our Providers

Frequently Asked Questions

Dialysis removes waste when the kidneys are not working properly. Therapeutic Plasma Exchange removes and replaces the plasma portion of blood to lower harmful antibodies, inflammatory proteins, or certain circulating toxins. The goals and medical indications are different.

The number of sessions depends on your diagnosis, symptom severity, and response. Acute cases may require a short series of 3 to 5 treatments. Chronic or autoimmune conditions often begin with 5 to 7 sessions, then adjust based on symptom trends and follow-up labs.

When performed by trained medical providers, TPE is generally well tolerated. During treatment, your blood circulates through a machine that separates and replaces plasma. You may feel cool or notice mild tingling from temporary calcium shifts. We monitor vital signs closely throughout your session.

Yes. We offer secure telehealth visits for patients worldwide, along with in-person care at our clinic in Tustin, California. Many patients visit us from across Orange County, including Irvine, Santa Ana, Orange, Costa Mesa, and Anaheim.

We accept most PPO insurance plans. Coverage varies by plan. We do not accept Medicare, Medicaid/Medi-Cal, or HMOs. When something isn’t covered, we’ll explain costs upfront and help you prioritize what matters most.

Have You Been Stuck in Flares That Won’t Fully Settle?

If you are living with ongoing inflammation, fatigue, or brain fog despite doing “everything right,” we can help you understand whether TPE is appropriate and how it may fit into a broader, physician-led plan.

Services We Are Known for

Explore our other services to heal,
feel your best and stay well for life.

Adrenal Fatigue
Recovery

If you feel drained, foggy, or “wired and tired,” there’s a reason. We look at your daily rhythm, hormone balance, and nutrient status, then create a steady plan to rebuild your energy without burning you out.

Integrative
Medicine

We bring the best of conventional and natural care together. Your story guides the testing. Your results guide the plan. The goal is simple: help you feel and function better, day by day.

Functional
Medicine

Symptoms have roots. We connect those dots with deeper labs, clear priorities, and a step-by-step plan that makes sense and fits your life.

Diagnostics and Functional Lab Testing

When basics don’t explain your symptoms, we dig deeper. From advanced bloodwork and stool tests to qEEG, HRV, ultrasound, ABI, and liver scan, we gather the right data so decisions are smarter.

Hypothyroid Treatment

TSH is only part of the picture. We evaluate full thyroid function, key nutrients, and related systems, then fine-tune medication, nutrition, and lifestyle so your energy and mood feel steady again.

IV Nutrient
Therapy 

Targeted infusions that replenish fast. Options can include vitamin C, B complex, minerals, NAD+, and glutathione to support energy, immunity, and recovery.

Ozone
Therapy

Oxygen-powered support for circulation, immune balance, and detox pathways. Often helpful for chronic fatigue and stubborn inflammation.

EBOO
Therapy

Extracorporeal Blood Oxygenation and Ozonation for higher-need cases. Designed to improve oxygen delivery and lower inflammatory burden under physician supervision.

Peptide
Therapy

Clinically used peptides that signal repair. We select the right options for goals like better recovery, sharper focus, deeper sleep, or metabolic support.

Hormone Replacement Therapy

Thoughtful HRT for women and men. We personalize dose, route, and timing using comprehensive labs and your real-world tolerance and goals.

Gut Health &
Digestive Healing

Bloating, pain, and food reactions have drivers. We balance the microbiome, repair the gut lining, and align food and lifestyle so your digestion and confidence improves.

Leaky Gut &
SIBO Treatment

Precise testing, clear stages, and practical support. We calm symptoms, restore motility, and rebuild barrier function so results last.

Elite Physical
Exams

Advanced diagnostics and personalized assessments uncover hidden health issues early and support optimized prevention, performance, and long-term vitality.

Autoimmune Treatment

Care that respects your immune system. We map flare patterns, reduce drivers like infections or food triggers, and protect long-term function with a plan you can maintain.

Longevity
Medicine

Add life to your years. We focus on prevention, body composition, cognition, and metabolic fitness with clear goals and periodic retesting to keep you on track.

Services We Are Known for

Explore our other services to heal,
feel your best and stay well for life.

Adrenal Fatigue
Recovery

If you feel drained, foggy, or “wired and tired,” there’s a reason. We look at your daily rhythm, hormone balance, and nutrient status, then create a steady plan to rebuild your energy without burning you out.

Integrative
Medicine

We bring the best of conventional and natural care together. Your story guides the testing. Your results guide the plan. The goal is simple: help you feel and function better, day by day.

Functional
Medicine

Symptoms have roots. We connect those dots with deeper labs, clear priorities, and a step-by-step plan that makes sense and fits your life.

Diagnostics and Functional Lab Testing

When basics don’t explain your symptoms, we dig deeper. From advanced bloodwork and stool tests to qEEG, HRV, ultrasound, ABI, and liver scan, we gather the right data so decisions are smarter.

Hypothyroidism Treatment

TSH is only part of the picture. We evaluate full thyroid function, key nutrients, and related systems, then fine-tune medication, nutrition, and lifestyle so your energy and mood feel steady again.

IV Nutrient
Therapy 

Targeted infusions that replenish fast. Options can include vitamin C, B complex, minerals, NAD+, and glutathione to support energy, immunity, and recovery.

Ozone
Therapy

Oxygen-powered support for circulation, immune balance, and detox pathways. Often helpful for chronic fatigue and stubborn inflammation.

EBOO
Therapy

Extracorporeal Blood Oxygenation and Ozonation for higher-need cases. Designed to improve oxygen delivery and lower inflammatory burden under physician supervision.

Peptide
Therapy

Clinically used peptides that signal repair. We select the right options for goals like better recovery, sharper focus, deeper sleep, or metabolic support.

Hormone Replacement Therapy

Thoughtful HRT for women and men. We personalize dose, route, and timing using comprehensive labs and your real-world tolerance and goals.

Gut Health &
Digestive Healing

Bloating, pain, and food reactions have drivers. We balance the microbiome, repair the gut lining, and align food and lifestyle so your digestion and confidence improves.

Leaky Gut &
SIBO Treatment

Precise testing, clear stages, and practical support. We calm symptoms, restore motility, and rebuild barrier function so results last.

Elite Physical
Exams

Advanced diagnostics and personalized assessments uncover hidden health issues early and support optimized prevention, performance, and long-term vitality.

Autoimmune Treatment

Care that respects your immune system. We map flare patterns, reduce drivers like infections or food triggers, and protect long-term function with a plan you can maintain.

Longevity
Medicine

Add life to your years. We focus on prevention, body composition, cognition, and metabolic fitness with clear goals and periodic retesting to keep you on track.