EBOO Therapy at Lam Clinic
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Our Functional Approach
Filtering and Re-Oxygenating Your Blood So Your Whole Body Can Reset and Recover

Many of our patients come to us with long-lasting fatigue, brain fog, inflammation, or post-viral symptoms that have not improved enough with standard care. They are looking for a structured, medical way to lower the burden on their body so other treatments can work better.
EBOO therapy (Extracorporeal Blood Oxygenation and Ozonation) is an advanced form of ozone therapy that filters, oxygenates, and ozonates your blood outside your body, then returns it through a closed, sterile system.
At Lam Clinic, we use EBOO as part of a comprehensive functional medicine approach to support your body’s natural healing processes, reduce inflammation, improve circulation, and help you recover from chronic illness.
In simple terms, a small amount of your blood leaves one arm, passes through a specialized dialysis-like filter where impurities are removed, is exposed to precisely measured medical-grade ozone while being oxygenated, and then returns to your other arm. The goal is to support healthy circulation, lower inflammatory byproducts, and improve the way your cells use oxygen.
Unlike basic ozone therapy that treats small batches of blood, EBOO provides simultaneous filtration and oxygenation of a much larger blood volume. This makes it a thoughtful option for chronic conditions involving systemic inflammation, toxin accumulation, poor circulation, or immune dysfunction.
Foundations of Care
The Four Pillars of
EBOO Therapy at Lam Clinic
Our EBOO therapy plans are built around four key pillars so treatment feels safe, understandable, and truly worth the time you invest.
Safety and Readiness First
We carefully review your history, cardiovascular status, clotting risk, medications, and key labs so we only move forward with EBOO when it is a safe and appropriate next step for your body.
Comprehensive Filtration and Oxygenation
We use a closed, dialysis-like system to gently filter, oxygenate, and ozonate your blood while you rest in a comfortable setting under continuous monitoring by our medical team.
Nutrient and Detox Support Around Each Session
We pair EBOO with hydration guidance, targeted IV nutrients, and simple at-home steps so your body can process the treatment more smoothly and you feel as stable as possible afterward.
Ongoing Tracking and Long-Term Planning
We follow your energy, symptoms, and key markers over time to adjust session frequency, stack EBOO with other therapies when helpful, and build a realistic maintenance plan that fits your life.
Patient Profiles
Who May Benefit from
EBOO Therapy?
EBOO therapy at Lam Clinic serves patients dealing with chronic health challenges that haven’t responded adequately to conventional approaches. EBOO is also for those who are seeking to optimize their health and wellness and focus on longevity.
Our functional medicine framework ensures EBOO fits your specific situation rather than applying a one-size-fits-all protocol.

You may benefit from EBOO if you experience:
- Persistent fatigue despite adequate sleep and nutrition
- Post-viral syndrome or long COVID with lingering symptoms
- Chronic inflammatory conditions (arthritis, autoimmune, chronic pain)
- Recurrent infections or compromised immune function
- Poor circulation, cold extremities, or slow healing
- Heavy metal toxicity or high toxic burden from environmental exposures
- Brain fog, cognitive decline, or neuroinflammation
- Chronic Lyme disease or co-infections
- Mold illness or mycotoxin exposure
- Cardiovascular concerns with poor oxygen delivery
- Multiple chemical sensitivities or biotoxin illness
- Chronic inflammatory response syndrome (CIRS)
Common patient profiles:
- Executives and professionals with chronic stress-induced health decline
- Athletes seeking enhanced recovery and performance optimization
- Post-cancer patients looking for immune support and detoxification
- Individuals with complex chronic illness who’ve “tried everything”
- People pursuing preventive medicine and longevity optimization

Clinical Insights
Potential Benefits of EBOO Therapy:
What the Research Shows

EBOO therapy provides multiple therapeutic mechanisms that work together to support health. Understanding what EBOO can and cannot do helps set realistic expectations.
1. Enhanced Oxygenation
EBOO significantly increases oxygen delivery to tissues by:
- Improving red blood cell flexibility and microcirculation
- Enhancing oxygen release from hemoglobin to tissues (right-shift of the oxygen-dissociation curve)
- Increasing 2,3-DPG levels in red blood cells
Why it matters: Better tissue oxygenation supports cellular energy production, healing, reduced fatigue, and brain function.
2. Powerful Antioxidant System Activation
Ozone creates brief, controlled oxidative stress that triggers your body’s own antioxidant defenses through the NRF2 pathway:
- Increases glutathione (master antioxidant)
- Activates superoxide dismutase (SOD) and catalase
- Supports heat shock proteins (HSP) for cellular protection
Why it matters: Your body builds lasting antioxidant capacity instead of relying only on external supplements, supporting protection against oxidative stress and aging.
3. Immune System Modulation
EBOO influences immune function by:
- Stimulating beneficial cytokines (IL-2, IFN-gamma, TNF-alpha at therapeutic levels)
- Enhancing white blood cell and natural killer (NK) cell activity
- Reducing inflammatory cytokines when overactive (IL-6, IL-1β) and helping balance Th1/Th2 responses
Why it matters: EBOO can strengthen weak immunity and calm overactive immunity, which is helpful in both chronic infections and autoimmune patterns.
4. Anti-Inflammatory Effects
Inflammation reduction occurs through:
- Direct inactivation of inflammatory mediators
- Improved circulation and reduced tissue hypoxia
- Enhanced mitochondrial function and reduced cellular stress
- Lower overall oxidative stress and modulation of inflammatory cascades
Why it matters: Systemic inflammation reduction can support joint pain, stiffness, autoimmune symptoms, cardiovascular health, and metabolic function.
5. Detoxification Support
The filtration component of EBOO helps remove:
- Cellular debris and waste products
- Inflammatory byproducts
- Some heavy metals (modest effect)
- Microbial fragments and endotoxins
- Oxidized lipids and proteins
Why it matters: EBOO is not a replacement for full detox protocols, but it provides meaningful support for toxic burden reduction, especially when paired with other detox strategies.
6. Antimicrobial Effects
Ozone has direct effects against pathogens:
- Viral inactivation through lipid envelope disruption
- Bacterial membrane damage
- Fungal cell wall disruption
- Parasite stress
Why it matters: This may be particularly valuable for chronic infections (such as Lyme, Epstein-Barr, or mold-related illness) where pathogens evade normal immune responses.
While EBOO is a newer iteration of ozone therapy, substantial research exists on ozone’s therapeutic mechanisms and clinical applications.
Recent research highlights:
- A 2021 study found that oxygen-ozone autohemotherapy reduced symptoms in chronic fatigue patients, suggesting benefit for persistent fatigue.
- A 2023 study showed ozone therapy boosted antioxidants while lowering oxidative damage in patients with inflammatory conditions, supporting the antioxidant activation mechanism.
- A 2022 study in the International Journal of Molecular Sciences reported beneficial effects of blood ozone therapies on inflammatory disorders, providing evidence for systemic inflammation reduction.
Research limitations: Most EBOO-specific research comes from European medical literature and clinical case series rather than large randomized controlled trials. The FDA notes this research gap while acknowledging ozone’s biological mechanisms are well-established. At Lam Clinic, we base protocols on the best available evidence while being transparent about limitations.
Important disclaimers:
- EBOO is not FDA-approved for treating specific diseases.
- EBOO is not a cure for any condition.
- Results vary significantly between individuals.
- Outcomes depend on overall health status, root causes, and consistency with comprehensive treatment plans.
- Some uses are based on clinical experience rather than large-scale controlled trials.
- We provide EBOO as part of integrative, physician-supervised functional medicine.
Our Healing Process
How EBOO Therapy Works at Lam Clinic Using the Lam Method™
Many people who come to us for EBOO feel worn down and unsure what else to try. They want a plan that makes sense of their symptoms and uses EBOO in a careful, coordinated way.
EBOO therapy is generally well-tolerated when administered correctly under physician supervision. Understanding potential side effects and our safety protocols helps you make informed decisions.
At Lam Clinic, EBOO is part of a complete plan led by physicians who understand autoimmune, toxin-related, and complex chronic illness. We use the Lam Method™ so EBOO is done at the right time, with the right support, and for the right reasons.
Here is how it works at Lam Clinic:

1. Reveal Root Causes
Before we begin, we learn why you feel the way you do and whether EBOO therapy is the right step for you.
We:
- Listen to your story and review medications, supplements, and past labs.
- Look at sleep, stress, food, movement, and daily exposures.
Map your NeuroEndoMetabolic (NEM) Stress Response to see which circuits are under strain instead of chasing single symptoms.
Six circuits we check:
- Hormone Circuit (adrenals, thyroid, reproductive organs)
Signs may include fatigue, sleep trouble, weight changes, hot flashes, and low libido. - Bioenergetics Circuit (thyroid, pancreas, liver)
Often tied to afternoon crashes, cravings, belly fat, or cholesterol shifts. - Detoxification Circuit (liver, immune system, tissue spaces)
Can show up as puffiness, sensitivity to medications or supplements, or a history of mold or chemical exposure. - Inflammation Circuit (immune system, microbiome, gut)
Often involved in bloat, food reactions, joint aches, skin flares, and post-viral issues. - Neuroaffect Circuit (gut, brain, stress nerves)
Commonly linked with brain fog, low mood, worry, or poor sleep. - Cardionomic Circuit (heart and autonomic nerves)
Associated with palpitations, fast heart rate, breathlessness, or dizziness on standing.
Initial consultation (virtual or in person)
We start with about a 60-minute visit to:
- Review your health history and current symptoms.
- Discuss what you have already tried and how your body responded.
- Evaluate whether EBOO is appropriate for you.
- Talk through expected timeline, outcomes, and cost options.
- Order pre-treatment lab work when needed.
You leave knowing whether EBOO is a good fit, what testing you need before starting, expected treatment frequency, and your general timeline.
Pre-treatment screening and labs
Safety begins before your first session. We:
- Take a detailed medical history and medication review.
- Screen for G6PD enzyme deficiency (to prevent hemolysis in at-risk individuals).
- Order focused labs such as CBC, CMP, kidney and liver panels, coagulation screen, inflammatory markers, and other tests when appropriate.
- Review results and provide safety clearance or address concerns before starting.
Pre-treatment preparation
To help you feel stable during treatment, we ask you to:
- Complete all required lab testing.
- Hydrate well (about 8–10 glasses of water) the day before and morning of treatment.
- Eat a protein-rich meal 1–2 hours before your session (no fasting).
- Take your regular medications unless we advise otherwise.
- Avoid alcohol for 24 hours before treatment.
- Wear comfortable clothing with sleeves that roll up easily.
- Bring something to do (book, tablet, laptop) during your session.
You may also bring:
- Your current medication and supplement list.
- Recent lab results.
- A list of questions or concerns.
- A water bottle and any simple entertainment for the treatment time.
If safety labs raise concerns, we address those first so you can move forward with confidence. This step shows whether EBOO therapy is appropriate and what to optimize first.

2. Rebuild Systems
Now we tailor EBOO to your needs and move at a pace your body can handle.
Personalized EBOO plan
Your doctor designs a plan that covers:
- How many EBOO sessions you may need.
- How far apart they should be.
- Filtration goals and oxygenation settings based on your history, labs, and tolerance.
Safety first during treatment
During your sessions, we follow strict safety protocols:
- Sterile, single-use equipment for every session.
- Medical-grade ozone generators with precise concentration control.
- Closed-system technique so ozone never enters room air.
- Continuous monitoring of vital signs.
- Careful anticoagulation (heparin) management.
- Two IV lines placed (one in each arm) by experienced Registered Nurses or medical professionals.
- Physician oversight with immediate response capability if needed.
Your EBOO treatment session
Total visit time is usually about 2 hours, including setup and monitoring.
- Arrival and preparation (15–20 minutes):
- Check-in with medical staff.
- Vital signs (blood pressure, pulse, temperature, oxygen saturation).
- Brief health status check.
- Hydration support if needed.
- Getting comfortable in a private treatment room.
- IV line placement (10–15 minutes):
- Two IV lines placed, one in each arm.
- Lines secured and tested for proper flow.
- EBOO treatment (around 50 minutes):
- System primed with sterile saline.
- Blood flow initiated at a controlled rate.
- Continuous filtration, ozonation, and oxygenation of your blood in a closed loop.
- Vital signs monitored throughout.
- Staff checks on you regularly and adjusts comfort measures as needed (blankets, position, entertainment).
- What it feels like:
- Similar to donating blood or receiving dialysis.
- Minimal discomfort after IV placement.
- Possible mild warmth or tingling from the ozone effect.
- Most patients read, work on a device, watch videos, or rest comfortably.
- Nutrient replenishment phase (15–20 minutes):
At Lam Clinic, we support your body right after EBOO with targeted IV nutrients to assist detoxification and recovery. Standard post-EBOO nutrient infusion may include:- Vitamin C – powerful antioxidant support to help neutralize free radicals, enhance immune function, and support collagen synthesis.
- Glutathione – master antioxidant that supports liver detoxification, cellular protection, and processing of oxidative signaling triggered by ozone.
- Magnesium – supports muscle relaxation, energy production, cardiovascular function, and can help prevent post-treatment cramping or fatigue.
- B-complex vitamins – support energy metabolism, nervous system function, and cellular regeneration.
- Why this matters: EBOO creates therapeutic oxidative stress that activates your healing systems. Providing high-quality nutrients immediately gives your body the raw materials it needs to complete the healing process, maximize benefits, and minimize detox discomfort.
- Treatment completion and monitoring (15–20 minutes):
- System flushed with saline to return all blood.
- IV lines removed.
- Post-treatment vital signs checked.
- Brief rest period to ensure stability.
- Aftercare instructions given and your next session scheduled when appropriate.
Smart stacking and comfort
Around your EBOO sessions, we may:
- Pair treatment with IV nutrients, targeted supplement plans, and simple lifestyle tools to support mitochondria, detox pathways, and immune balance.
- Offer rate control, warm blankets, hydration coaching, and a calm environment so you feel as comfortable as possible.
The goal in this stage is clear: use EBOO to improve oxygenation and filtration while keeping you safe, supported, and steady.

3. Renew Your Future
Good results should last. We help you keep them and understand what to expect along the way.
Post-treatment monitoring and follow-up
Right after each session we:
- Monitor you before discharge.
- Review your vital signs and how you feel.
- Provide clear at-home instructions.
- Set up follow-up protocols and symptom tracking.
Over time, we follow practical markers like energy and sleep scores, HRV, and key labs so changes are guided by data, not guesswork.
Common and expected responses
It is normal to notice some short-term responses as your body processes treatment.
Immediate (during or right after treatment):
- Mild warmth or tingling sensation (a normal ozone effect).
- Slight fatigue or relaxation.
- Occasional mild lightheadedness (usually resolves quickly).
- Vein tenderness at IV sites (similar to any IV procedure).
24–72 hours after treatment (detox responses):
- Brief flu-like symptoms (Herxheimer reaction) that may indicate toxins or pathogens being cleared.
- Mild fatigue as your body processes treatment effects.
- Slight headache, often preventable with good hydration.
- Temporary increase in symptoms before improvement (“healing crisis”).
- Changes in bowel movements.
These are generally positive signs that your body is responding to treatment. They typically resolve within 1–3 days and tend to lessen with subsequent sessions.
Less common side effects
- Nausea (usually mild and manageable with slower flow rates).
- Bruising at IV insertion sites.
- Transient dizziness.
- Mild chest tightness (rare, requires immediate attention).
- Temporary changes in blood pressure.
Rare but serious risks
With proper protocols, these are extremely rare, but we still screen and monitor for them:
- Hemolysis (red blood cell breakdown) in unscreened G6PD-deficient patients.
- Prevention: G6PD testing before the first treatment.
- Infection at IV sites.
- Prevention: strict sterile technique.
- Air embolism.
- Prevention: closed-system technique with air detectors.
- Allergic reaction to heparin (the anticoagulant used during the procedure).
- Prevention: pre-treatment allergy screening.
- Adverse cardiovascular events.
- Prevention: proper cardiovascular screening.
Managing side effects
If you experience any concerning symptoms during or after EBOO:
- Inform our medical team immediately during treatment.
- Call our clinic line within 24 hours after discharge if you have questions or milder delayed symptoms.
- Seek emergency care for severe symptoms such as chest pain, severe shortness of breath, or signs of a severe allergic reaction.
Long-term planning
As we see how your body responds, your long-term plan may include:
- A simple maintenance schedule or “as needed” EBOO plan if it clearly helps.
- Ongoing support with nutrition, sleep, movement, and stress tools.
- Periodic lab checks to track inflammation, organ function, and risk markers.

Proven Excellence
Why Choose Lam Clinic
Lam Clinic has more than 25 years of experience caring for people with complex, stress-related, and chronic illness. EBOO therapy here is always guided by the Lam Method™ and the NEM Stress Response model, so we look at your hormones, immune system, circulation, detox, and nervous system together before deciding if EBOO is appropriate.
Our team in Tustin takes time to review your history, labs, medications, and past treatments. Many patients come to us after being told their labs are “normal” while they still feel fatigued, inflamed, or foggy.
We use targeted testing, HRV and autonomic assessments, and safety screening, including G6PD and cardiovascular review, to decide if EBOO is a safe and clinically meaningful option. If it is not the right fit, we tell you directly and suggest alternatives.
Every EBOO session is physician-led and nurse-supervised, using sterile single-use supplies, a closed system, careful anticoagulation, and continuous vital sign monitoring.
After treatment, we routinely support you with IV nutrients such as vitamin C, glutathione, magnesium, and B vitamins to help your body handle oxidative stress and detoxification. EBOO is never offered as a stand-alone procedure; it is used as one part of a coordinated functional medicine plan designed for your specific situation.
Frequently Asked Questions
What exactly is EBOO therapy and how does it differ from regular ozone therapy?
EBOO stands for Extracorporeal Blood Oxygenation and Ozonation. It’s an advanced form of ozone therapy that treats approximately 2 liters of blood continuously over 60-90 minutes, compared to standard ozone autohemotherapy (MAH) which treats only 200-250ml in batches. EBOO also includes a filtration step that removes debris and toxins. Think of it as the difference between spot-cleaning a carpet versus professionally cleaning the entire carpet—both use similar principles, but EBOO is more comprehensive and treats a much larger volume.
Who is a good candidate for EBOO Therapy?
People with low energy, brain fog, slow recovery after illness, frequent flares, or circulation concerns often ask about EBOO. You should be medically stable, able to hydrate well, and comfortable sitting for 60–90 minutes. We confirm fit with a review of your history, medications, and key labs.
Who should not have EBOO?
We may delay or avoid EBOO if you have uncontrolled bleeding disorders or heparin intolerance, severe anemia, unstable heart failure or rhythm issues, active fever, or if you are pregnant. If EBOO is not right today, we will create a safer step-by-step plan.
How do I prepare for my first session?
- Hydrate well the day before and morning of your visit
- Eat a protein-rich meal 1–2 hours before
- Follow our instructions about medications/supplements, especially those that affect clotting
- Wear comfortable clothing with sleeves that roll up
- Bring recent labs and your med/supplement list
How many EBOO sessions will I need?
Most patients start with 4-8 weekly sessions, then transition to maintenance based on their condition and response. Chronic complex conditions may require more initial sessions (8-12). Maintenance varies widely—some patients benefit from monthly sessions, others need treatment only quarterly or seasonally. We use objective markers (HRV, labs, symptom scores) alongside your subjective experience to determine the optimal schedule for you.
Can I work or exercise after EBOO therapy?
Most patients can resume normal activities immediately. We recommend avoiding intense exercise for 24 hours after your first session to see how your body responds. Mental work (computer work, meetings) is generally fine. Listen to your body—if you feel tired, rest. If you feel energized, you can be normally active. Hydration is crucial in the first 24 hours post-treatment.
Can I combine EBOO with other treatments?
Yes! EBOO works synergistically with other therapies. We commonly pair it with IV nutrient therapy (vitamin C, glutathione, B-complex), targeted supplementation, hormone optimization, peptide therapy, and lifestyle modifications.
What should I expect to feel after EBOO treatment?
Many people feel more clear-headed or energized soon after a session. Others notice mild tiredness or “processing” for 24–48 hours, with possible temporary warmth, lightheadedness, or bowel changes. These responses usually pass within a few days. By the second or third session, many patients report better energy, less pain, deeper sleep, and clearer thinking.
Are there any side effects or risks with EBOO therapy?
Mild, short-term effects can include headache, brief fatigue, lightheadedness, nausea, vein tenderness, bruising, or temporary blood-pressure changes. Rare but more serious risks include hemolysis in people with G6PD deficiency, infection, air embolism, allergic reaction to heparin, or cardiovascular events. At Lam Clinic we minimize these risks through G6PD testing, cardiovascular screening, strict sterile and closed-system technique, and continuous monitoring.
Is EBOO therapy safe?
Safety is our priority. At Lam Clinic you receive physician-led oversight, trained nursing care, single-use sterile supplies, continuous vitals monitoring, and a clear anticoagulation protocol. We screen for contraindications and review up-to-date labs before starting.
Will EBOO cure my condition?
EBOO is not a cure for specific diseases. It’s one part of a root-cause, integrative plan to help you feel and function better. Results vary by person, health status, and consistency with the full care plan.
How is EBOO different from dialysis?
EBOO is not kidney dialysis and does not replace kidney function. It’s a wellness therapy designed to improve oxygenation and filter select byproducts in a closed, sterile loop.
How much does EBOO therapy cost at Lam Clinic?
Costs depend on your personalized plan, the number of sessions, and any supportive therapies. We’ll review options, package pricing, and payment plans during your consultation.
Do you accept insurance for EBOO therapy?
EBOO is not covered by insurance. We offer transparent pricing and can provide documentation you may submit to your plan, though reimbursement is not guaranteed.
How soon can I book, and do you offer virtual consults?
Yes. We offer in-person care in Tustin and virtual consults to review your history, labs, and goals. From there, we’ll map your safest, most effective starting point and schedule your first session.
Where are you located, and what visit options do you offer for EBOO therapy?
We perform EBOO treatments in person at Lam Clinic in Tustin, serving Orange County and the surrounding areas. You can also start with a telehealth visit from home or work, where we review your history, labs, and goals, and guide you through any forms or testing needed before you come in for treatment.
Ready To Explore EBOO Therapy
With A Team That Listens?
Tell us what you’re going through. We’ll help you understand whether EBOO at Lam Clinic is a good fit for your situation and where it might fit in your overall care plan. You can also request details about pricing and treatment options. A Treatment Coordinator will contact you shortly. For immediate help, call 714-709-8000.
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